The museum functions in a double-storied heritage mansion that reflects ancient architectural elegance. The heritage building itself is a show piece of Kerala style architecture in construction, in which the Arya Vaidya Chikitsasala (present Charitable Hospital) started in 1924. The ground floor of the museum explains the ancient education system, important social changes happened in Malabar region, etc. The rich collection of photographs, graphics, drawings, and write-ups exhibited here conveys the essence of the history of Arya Vaidya Sala and Ayurveda in general. The eight galleries within the museum display the academic and educational models of Ayurveda during the 18th and 19th centuries. Besides, the historical remnants of utensils for medicine manufacturing, potteries, wooden barrels, and planks for Ayurveda therapies, are arranged here for the visitors to have a comprehensive picture of the transition of Ayurveda from ethnic to enterprise.

The museum caters to the interests of people from all walks of life - researchers, Ayurveda students, practitioners, historians, university scholars, school-going children, and homemakers.